Detection of HCV associated markers in the serum of spouses of patients with type C chronic liver disease.

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概要

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• To evaluate the inter-spouse transmission as one of the infectious routes of HCV. 48 patientspouse pairs were studied. Out of 48 patients with type C chronic liver disease, 14 (29%) had spouses with seropositive HCV markers.<BR>Eight spouses had C100-3 antibody and core antibody. They had also HCV RNA and showed abnormal liver function tests. Other 6 spouses had core antibody without C100-3 antibody. Two of these 6 spouses had HCV RNA and showed high value of ZTT test. HCV genotype was matched within 7 patient-spouse pairs and different in other 3 pairs. These results suggest that inter-sponse transmission may exist certainly as one of the infectious routes of HCV, but other environmental factors also may not be ignored.

著者

• 木村 公憲

  山梨医科大学第1内科

関連論文

• Detection of HCV associated markers in the serum of spouses of patients with type C chronic liver disease.

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