慢性肝疾患における^<99m>TcDTPA-HSA肝血流シンチグラフィーの臨床的有用性について
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概要
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<SUP>99m</SUP>Tc-DTPA-HSA scintiangiography was performed in 81 cases of viral chronic liver disease, and a time-activity curve (TAC) of the liver was classified into three types (I, II, III). Furthermore, portal component of the total hepatic blood flow was calculated. The results were compared with those of <SUP>99m</SUP>Tc-phytate scintiangiography. The TAC type changed from I through III according to the histological developement of the liver. Esophageal varices was seen frequently in patients of type III, and in none of type I. The portal component significantly decreased in the order of chronic hepatitis without lobular distortion, with lobular distortion, and liver cirrhosis. However, the portal component obtained by using <SUP>99m</SUP>Tc-phytate did not show a significant difference between chronic hepatitis without and with lobular distortion. <SUP>99m</SUP>Tc-DTPA-HSA scintiangiography was thought to be an useful diagnostic procedure in patients with chronic liver disease.
- 社団法人 日本肝臓学会の論文