腫瘍内フィブリノ-ゲン消費を示した巨大な肝血管腫の1治験例

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A 51-year-old woman with a cavernous hemangioma of the liver and hypofibrinogenemia was presented. Measurements of the plasma coagulation factor revealed a decreased fibrinogen concentration and an increase of fibrinogen degradation products. Platelet count and prothrombin time were within normal limit. Fibrinogen concentration and FDP were improved slightly by the heparinization. 131I-Fibrinogen was accumulated at the site of the tumor on the liver scintigram, this accumulation corresponded with defect of the liver scintigram with 99mTc-phytate. A consumption of fibrinogen in the hemangioma was considered. The resected tumor by extended right lobectomy of the liver was 2500g. in weight and 17×15×16cm in size. Fibrin was histopathologically proved in the section of the tumor by phosphotangstic acid hematoxylin staining. Fibrinogen concentration and FDP was normalized respectively after the surgery.
社団法人日本肝臓学会の論文