原発性肝癌の病理形態学的研究--肝細胞癌の肝内血管系における腫瘍血栓について

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The purpose of this paper was to explain a significance of intravascular tumor thrombus in hepatocellular carcinoma (HCC).<BR>The relationship between intravascular tumor thrombus and growth fashion, the presence or absence of cirrhosis, distant metastasis and splenomegaly was studied in 61 autopsy cases of HCC.<BR>In 33 cases, tumor thrombus was seen in the portal veins and it was seen in the hepatic veins in one case. In 22 cases, it was seen in both portal and hepatic veins. 5 cases had no intravascular tumor thrombus. In concern to growth fashion, the intravascular tumor thrombi were recognized more frequently in the infiltrative and mixed types rather than the expansive types. Tumor thrombus in the portal veins was recognized frequently in the cases with cirrhosis, and tumor thrombus in the hepatic veins was frequent in the cases without cirrhosis.<BR>Close relationship between tumor thrombus in the portal veins and distant metastasis was not recognized, but some relationship was seen between metastasis and tumor thrombus.<BR>The mean weight of the spleen increased in the cases with both cirrhosis and tumor thrombus in the portal veins.
社団法人日本肝臓学会の論文