HISTOCHEMICAL STUDIES ON PATHOLOGIC CALCIFICATION
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概要
- 論文の詳細を見る
1. Itried to modifize the Kossa's method and by the foregoing procedure in oxalic acid solution, contrived better method for demonstration of calcium deposits in tissue.2. With my new method and several histochemical procedures, it has been found that the fundamental matrix of pathologic calcification is mucopolysacchride degeneration.3. The mucopolysaccharides by influence of some tissue damage, are lost their colloidal property and precipitated or coagulated, this degeneration of muco- polysaccharides associate with ionized calcium or calcium salts in tissue fluid and form mucopolysaccharide calcium complex.As the ratio of calcium salts which are attracted from surrounding tissue fluid increase, the mucopolysaccharide part as fundamental matrix of calcifica- tion decreases its quantity, and then, is formed the complete inorganic calcium deposit.
- The Keio Journal of Medicineの論文