BIOCHEMICAL BASIS FOR NARCOTIC TOLERANCE AND PHYSICAL DEPENDENCE

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概要

• 論文の詳細を見る

• Despite long and extensive efforts, biochemical basis for the narcotic tolerance and physical dependence is still unknown. It appears, however, that the development of tolerance to, and physical dependence on, narcotics is related to protein synthesis mechanisms in the central nervous system, which results in alterations in either neuro-transmitter mechanism(s) or receptor protein or both. Recent advances in studies on protein synthesis and the successful demonstration of "opiate receptor" may shed light on the biochemical nature of these intriguing phenomena.

• The Keio Journal of Medicineの論文

著者

• LEE CHENG-YI

  Department of Pharmacology, Michigan State University

• AKERA TAI

  Department of Pharmacology, Michigan State University

関連論文

• BIOCHEMICAL BASIS FOR NARCOTIC TOLERANCE AND PHYSICAL DEPENDENCE

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