The effect of starvation on enzymes of purine catabolism in mouse liver.

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概要

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• The effect of starvation for 24 and 48 hours on the enzymes of purine nucleotide catabolism, i.e. 5'-nucleotidase, AMP deaminase, adenosine deami-nase, purine nucleoside phosphorylase, xanthine oxidase and guanase, has been examined with the mouse liver extract. Among them, 5'-nucleotidase activity increased by about 2 times after 24 and 48 hours of starvation. AMP deaminase decreased by about 18 and 12% after 24 and 48 hours of starvation, respectively. Adenosine deaminase increased by about 9 and 20% after 24 and 48 hours of starvation, respectively. On the other hand, purine nucleoside phosphorylase, xanthine oxidase and guanase activities did not change sig-nificantly. It is concluded that acute starvation may cause the imbalance of purine nucleotide metabolism in the liver.

• The Keio Journal of Medicineの論文

著者

• KIZAKI HARUTOSHI

  Department of Biochemistry, School of Medicine, Keio University

関連論文

• The effect of starvation on enzymes of purine catabolism in mouse liver.

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