HISTOLOGIC STUDIES ON LIPOGRANULOMA
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概要
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From the histologic studies in seventeen cases of lipogranuloma, two types, the typical and the atypical type, were differentiated. Among the seventeen cases, twelve cases were typical lipogranuloma cases, while five were atypical cases. The atypical lipogranuloma is characterized by its cyst formation. Some observers have the opinion that the cyst formation occur in later stages, however, in my cases, cyst formation was even found in early stages. It is considered, to the author's opinion, that the lipogranuloma with cysts should be differentiated from the typical type. Further, between these two types of lypogranuloma tinctorial differences were noticed by the lipide staining method.The causative mechanism of the formation of lipogranuloma was considered to be not a simple one. When a certain cause, either traumatic or inflammatory, etc., happen to act in an individual with the disposition, first lesion occurs in the vessel, which leads the degeneration and necrosis of the fat tissue. The liberated fat also degenrates, however, in this case whether lipase is closely connected with this degeneration or not is not clear. Around this degenerated fat arises the productive reaction chiefly consisted of giant cells, epitheloid cells and histiocytes, and finally fibrosis occurs.In one case bone formation was found in the wall of the cyst.The author wish to express his gratitude to Prof. Tadayoshi Kobayashi for suggesting this investigation as well as for constant guidance in the course of the work. Thanks are also due to Prof. Yoshio Kusama for reading and revising the manuscript.
- The Keio Journal of Medicineの論文
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関連論文
- THE HISTOPATHOLOGICAL AND HISTOCHEMICAL STUDIES ON THE ADRENAL CORTEX OF MYELOIC LEUKEMIA AND APLASTIC ANEMIA
- HISTOLOGIC STUDIES ON LIPOGRANULOMA