Plasma Antidiuretic Hormone in Patients with Delayed Endolymphatic Hydrops
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概要
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Plasma antidiuretic hormone (ADH) levels were studied in 105 patients with unilateral profound deafness, including 31 with delayed endolymphatic hydrops, 53 with sudden deafness, 6 with temporal bone fracture and/or perilymphatic fistula, and 15 with juvenile unilateral profound deafness. As previously reported, high plasma ADH levels were noted in patients with delayed endolymphatic hydrops. ADH levels were also elevated in juvenile unilateral profound deafness. No marked rise in plasma ADH level was observed in the other disease groups. In the present study, high plasma ADH levels were frequently observed in those with a long duration of disease. Delayed endolymphatic hydrops is known to develop years to decades after the onset of profound deafness. Although the pathogenesis of this process remains unclear, an increase in the plasma ADH level might be one of the underlying mechanisms of delayed endolymphatic hydrops.
- 一般社団法人 日本めまい平衡医学会の論文