Molecular Pharmacology of Voltage-Dependent Calcium Channels
スポンサーリンク
概要
- 論文の詳細を見る
Voltage-dependent Ca<SUP>2+</SUP> channels serve as the only link to transduce membrane depolarization into cellular Ca<SUP>2+</SUP>-dependent reactions. A wide variety of chemical substances that have the ability to modulate Ca<SUP>2+</SUP> channels have been demonstrated both for their clinic utility and for importance in elucidating the molecular basis of various biological responses. Recently, introduction of molecular biology to pharmacology has brought a great deal of information about the molecular basis of drug action in Ca<SUP>2+</SUP> channels. In this review, we attempt to overview recent progress in understanding the interactions between Ca<SUP>2+</SUP> channels and their blockers, namely Ca<SUP>2+</SUP> antagonists, from a molecular and structural point of view.
- 社団法人 日本薬理学会の論文
著者
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Mori Yasuo
Institute of Molecular Pharmacology and Biophysics, University of Cincinnati College of Medicine
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Mikala Gabor
Institute of Molecular Pharmacology and Biophysics, University of Cincinnati College of Medicine
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Varadi Gyula
Institute of Molecular Pharmacology and Biophysics, University of Cincinnati College of Medicine
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Kobayashi Tsutomu
Institute of Molecular Pharmacology and Biophysics, University of Cincinnati College of Medicine
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Koch Sheryl
Institute of Molecular Pharmacology and Biophysics, University of Cincinnati College of Medicine
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Wakamori Minoru
Institute of Molecular Pharmacology and Biophysics, University of Cincinnati College of Medicine
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Schwartz Arnold
Institute of Molecular Pharmacology and Biophysics, University of Cincinnati College of Medicine
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Schwartz Arnold
<I>Institute of Molecular Pharmacology and Biophysics, University of Cincinnati College of Medicine</I>
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Wakamori Minoru
<I>Institute of Molecular Pharmacology and Biophysics, University of Cincinnati College of Medicine</I>
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Mori Yasuo
<I>Institute of Molecular Pharmacology and Biophysics, University of Cincinnati College of Medicine</I>