EFFECTS OF 1-METHYL-5-CHLOROINDOLINE METHYLBROMIDE (S-6) ON RENSHAW CELLS OF CATS

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概要

• 論文の詳細を見る

• Effects of 1-methyl-5-chloroindoline methylbromide (S-6) on Renshaw cells were investigated in cats anesthetized with pentobarbital sodium. S-6 proved to have little effect on spike discharges of Renshaw cells when administered intravenously, but the agent electrophoretically applied revealed excitatory effects which resembled the action of methacholine and such effects were blocked by intravenous administration of atropine. It was concluded that (1) S-6 is impermeant to the blood brain barrier and (2) the excitatory action of S-6 on Renshaw cells is muscarinic in nature.

• 社団法人 日本薬理学会の論文

著者

• IRIKURA TSUTOMU

  Kyorin Central Research Laboratories

• OHKUBO Hideo

  Kyorin Chemical Laboratory

• HIRAYAMA Takashi

  Kyorin Chemical Laboratory

• NISHINO Keigo

  Kyorin Chemical Laboratory

• IRIKURA Tsutomu

  Kyorin Chemical Laboratory

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• EFFECTS OF 1-METHYL-5-CHLOROINDOLINE METHYLBROMIDE (S-6) ON RENSHAW CELLS OF CATS
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