PHARMACOLOGICAL PROFILE OF A NEW CYCLOHEPTEN SYMPATHOMIMETIC AGENT, COMPOUND 70-352

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概要

• 論文の詳細を見る

• Pharmacological profile of a new sympathomimetic agent, compound 70-352, is reported herein. This compound was found to directly stimulate a-adrenergic receptors in the cat, guinea pig, rabbit and rat. Activity was similar to that of noradrenaline (NA) but it was only 0.032% as potent as NA on isolated rat uterus. Duration of action of the compound was, however, much longer. Compound 70-352 had no effect on the central nervous system and the acute LD<SUB>50</SUB> in mice was 1000.0 mg/kg i.p.

• 社団法人 日本薬理学会の論文

著者

• SINGH G.B.

  Division of Pharmacology, Central Drug Research Institute

• SRIMAL R.C.

  Division of Pharmacology, Central Drug Research Institute

• DHAWAN B.N.

  Division of Pharmacology, Central Drug Research Institute

関連論文

• PHARMACOLOGICAL PROFILE OF A NEW CYCLOHEPTEN SYMPATHOMIMETIC AGENT, COMPOUND 70-352
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