EFFECTS OF SOME SYMPATHOMIMETIC AMINES ADMINISTERED INTRAVENTRICULARLY ON RABBIT'S EEG
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In the previous paper (1), the author reported that the intraventricular administration of adrenaline induced both the arousal and the restng pattern of EEG in rabbits, and that the intraventricular pretreatment of <I>alpha</I>-adrenergic blocking agents suppressed the appearance of the resting pattern, while the resting or sleep pattern appeared more markedly following the pretreatment with <I>beta</I>-adrenergic blocking agents. These results suggest that the EEG resting pattern induced by the intraventricular administration of adrenaline may be dependent on its <I>alpha</I> action, and that there may be two contrasting effects on EEG depending on the <I>alpha</I> and the <I>beta</I> action of the catecholamine injected intraventricularly. In the present experiment, the author reevaluated these hypotheses by examining effects of the intraventricular administration of noradrenaline, phenylephrine and isoproterenol on rabbit's EEG. Modifications of the effects of intraventricularly administered adrenaline were also studied following the systemic pretreatment of dibenamine or reserpine.
- 公益社団法人 日本薬理学会の論文
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関連論文
- EFFECTS OF INTRAVENTRICULARLY ADMINISTERED ADRENALINE ON RABBITS EEG AND THEIR MODIFICATIONS BY ADRENERGIC BLOCKING AGENTS
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- EFFECTS OF SOME SYMPATHOMIMETIC AMINES ADMINISTERED INTRAVENTRICULARLY ON RABBIT'S EEG