EFFECT OF CHOLINOLYTIC HALLUCINOGENS ON ACETYLCHOLINE CONTENT OF CERTAIN PARTS OF RABBIT BRAIN

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概要

• 論文の詳細を見る

• The central stimulatory actions of atropine causing excitement, tremors and hallucinations in high doses are well known. Giarman and Pepeu (1) showed that atropine and hyoscine reduced the total acetylcholine content of brain. Further it has been suggested that among certain cholinolytic hallucinogens (like atropine and hyoscine), the psychotomimetic activity may be linked with an alteration in the total acetylcholine level of brain (2, 3). It is also known that rabbits are resistant to the central psychotomimetic actions of atropine which are commonly seen in man and other experimental animals with high doses of these drugs. It was therefore considered worthwhile to examine the effect of atropine and hyoscine on the acetylcholine content of different parts of rabbit brain.

• 社団法人 日本薬理学会の論文

著者

• MATIN M.A.

  Industrial Toxicology Research Centre, Chattar Manzil Palace

• VIJAYVARGIYA R.

  Department of Pharmacology, M.G.M. Medical College

• MATIN M.A.

  Industrial Toxicology Research Center, Chattar Manzil Palace

関連論文

• EFFECT OF CHOLINOLYTIC HALLUCINOGENS ON ACETYLCHOLINE CONTENT OF CERTAIN PARTS OF RABBIT BRAIN
• EFFECT OF CHOLINESTERASE INHIBITORS AND PAM ON THE RELEASE OF ACETYLCHOLINE FROM ISOLATED GUINEAPIG ILEUM
• CORRELATION BETWEEN ELECTROENCEPHALOGRAPHIC (EEG) EFFECTS AND ACETYLCHOLINE CONTENT OF BRAIN AFTER CHOLINOLYTIC HALLUCINOGENS

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