PHARMACOLOGICAL STUDY OF 1-(β-PHENYLETHYL) TRIAZOLO (4, 5-c) PYRIDINE HYDROCHLORIDE, A TRANQUILLIZING AGENT
スポンサーリンク
概要
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In an investigation of the pharmacological activities of a large number of substituted diaminopyridine and the corresponding imidazo- and triazolo pyridines it was found that imidazo- and triazolo (c) pyridines, in general, produced central depressant action and amongst these 1-(β-phenylethyl) triazolo (4, 5-c) pyridine hydrochloride (PCA9) showed relatively better sedative and tranquillizing effects in mice (1, 2). In view of the tranquillizing activity of PCA9 a study on some neuro-psychopharmacological and other pharmacodynamic effects of this compound was carried out to elucidate the pattern of activity and the results of which are embodied in the present communication.
- 社団法人 日本薬理学会の論文
著者
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AHMAD A.
Division of Pharmacology, Central Drug Research Inst.
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VOHRA M.M.
Dept. of Pharmacology, University of Alberta
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ACHARI G.
Division of Pharmacology, Central Drug Research Inst.