A FURTHER STUDY OF Cu<SUP>++</SUP> CHELATE OF KANAMYCIN

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概要

• 論文の詳細を見る

• In the previous paper (1), it was reported that kanamycin (KM), an antibiotic found by Umezawa <I>et al</I>. (2), formed a chelate with Cu<SUP>++</SUP> at a molar ratio of 2:1. The structure shown in Fig. 1-a was proposed for this chelate where the propylene diamine moiety of KM took part in the formation of the chelation compound. To confirm this structure, deoxystreptamine (DOSA) was prepared by hydrolysis of KM and a comparative study of Cu<SUP>++</SUP> chelates of DOSA and ethylene diamine (EDA) with that of KM was made by infrared spectroscopy and polarography.

• 社団法人 日本薬理学会の論文

著者

• 山辺 茂

  Research Institute, Kobe College

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