A NEW AUTOMATIC DEVICE FOR CONDITIONED REFLEX EXPERIMENT

概要

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In the process of evaluating psychotropic drugs, studying their effects on conditioned reflex is one of the inevitable means. To date, the experiment of even a simple conditioned reflex, such as a pole climbing method, requires a lot of time and effort of investigators, if they wish to trace drug effects on it continuously for a prolonged period of time. Moreover, training itself of animals is also much troublesome. The authors have developed a new equipment which can train the animals, test the reflex and record the results automatically. Much tedious and troublesome works of investigators have been thus eliminated by this device, especially when drug effects on conditioned reflex are examined continuosly over a prolonged period. In the present paper, the authors' method with this equipment is described and the effects of some tranquilizing agents on conditioned reflex are demonstrated with some interesting results obtained by the aid of this apparatus.
公益社団法人日本薬理学会の論文