ACTION OF SEVERAL ANTI-HISTAMINICS ON THE ISOLATED RAT PHRENIC-DIAPHRAGM PREPARATION

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概要

• 論文の詳細を見る

• Since Fourneau and Bovet (1) reported 2-<I>iso</I>propyl-5-methyl phenoxy-ethyl-diethylamine as a potent anti-histaminic, many publications on the central action of anti-histaminics have appeared during the last three decades. However, no report on the action of anti-histaminics to the neuromuscular junction has appeared, despite the fact that listlessness of the limbs occurs when a small dose of anti-histaminics is administered, as in the case of succinylcholine administration.<BR> In the present paper, the neuromuscular blocking property of several anti-histaminics was first screened, and then its mechanism of action was studied using rat phrenicdiaphragm preparation.

• 公益社団法人 日本薬理学会の論文

著者

• 滝内 武

  Department of Pharmacology, School of Medicine, Showa University

関連論文

• ACTION OF SEVERAL ANTI-HISTAMINICS ON THE ISOLATED RAT PHRENIC-DIAPHRAGM PREPARATION

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