ABSORPTION, DISTRIBUTION AND EXCRETION OF METHYLALCOHOL

概要

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Recently methylalcohol is attracting the attention of medical circle, because of many cases of its intoxication, but a lot of questions are still left unanswered as of its pharmacological action. About the distribution of methylalcohol in body and its ways of excretion, there are not so many reports as yet. As far as we know, S. Ueno (1) analysed the methylalcohol contents of various organs of corpses by its intoxication and found that most methylalcohol was contained in blood, and then came out in order of urine, bile, brain and stomach contents. A. Benedicenti (2) let the cats inhale methylalcohol of 3, 4 vol.% eight hours long, and recovered it in the organs as follows : blood, 0, 562g %; liver 0.207; brain 0.19; urine 0.528. According to M. Nicloux (3) and M. Neymark (4), methylalcohol remains in body longer than ethylalcohol. We made the same analysis systematically on more organs than they did.
公益社団法人日本薬理学会の論文