Inhibition of ifosfamide-induced urotoxicity by disulfiram in mice.
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概要
- 論文の詳細を見る
The effect of disulfiram on the urotoxicity induced by ifosfamide was studied in mice. Ifosfamide administered intraperitoneally to mice caused a dose-related increase in bladder weight within 48 hr of treatment. Disulfiram prevented ifosfamide-induced bladder damage when administered orally within 1 hr of ifosfamide treatment. The results indicate that disulfiram is an effective protective agent against bladder damage caused by ifosfamide treatment.
- 公益社団法人 日本薬理学会の論文
著者
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Sasaki Ken-ichi
Institute For Materials Research Tohoku University
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SASAKI Ken-ichi
Institute of Cancer Research, Tohoku College of Pharmacy
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ISHIKAWA Masaaki
Institute of Cancer Research, Tohoku College of Pharmacy
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TAKAYANAGI Yoshio
Institute of Cancer Research, Tohoku College of Pharmacy
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