加速廻転刺戟の血清カリウムに及ぼす影響

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By means of Prof. Hasegawas accelerating rotation apparatus, observation was made of the effects upon the serum potassium caused by the labyrinth stimulus and also the effects of them by sodium bicarbonate solution. In this experiment, normal dogs bilaterally labyrinthectomized dogs and the dogs to which sodium bicarbonate solution, had been injected all un-anaesthetized, were brought under the influence of accelerating rotation stimulus for 15, 30 and 60 minutes and the blood samples were collected every hour to be tasted for the content of serum potassium with Cobaltinitrite method. The follo-wing results were obtained. 1) In the normal dogs, the accelerating rotation stimulus caused a considerable, though tempo-rary, increase of the potassium. In other words in the 15 min. stimulus, the level of potassium reached its peak within 10 minutes after the application of the stimulation and in the 30 and 60 min. stimulus, the potassium level reached to the maximum immediately after the test. Then it tapered off with the lapse of time. The highest mark of all was reached in 60 min. test. 2) The dogs which had been given intravenous injection of 2cc per kg of sodium bicarbonate solution 2 or 3 days before the experiment or the dogs had been labyrinthectomized on both side a day before were tested likewise. Neither showed no such conspicuous change in the potassium content as shown in the normal dogs, irrespective of the length of the stimulation time. The difference of the potassium content during and after the stimulation upon each group of dogs with this accelerating rotation apparatus was closely measured and the conclusion was made that during the stimulation an increase was observed and after the test the content reduced to the original level with the infl-uence of reparation. On the basis of the above experiments, it is prsumed that the accelerating stimuli bring about sympathetic nervous disorder through labyrinth and the change in the amount endorses the assum-ption that the said solution will prevent the motion sickness.

加速廻転刺戟の血清カリウムに及ぼす影響

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