紫外線吸収性より見たる蝸牛神経中枢の核酸成分の研究
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概要
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By ultraviolet analysis, the author investigated the nucleic acids which is closely related to the function of nerve cells. (I) Method (1) Eextraction of nucleic acids. (2) Use of the following methods a) microphotometry by Olympus ultraviolet microscope b) direct ultraviolet microphotometry (II) Material Experimental animals used were rats in method (1) and guinea pigs in method (2). (III) Experimental conditions 1. normal state 2. with sound stimulation 3. State of Dihydrostreptomycin intoxication (IV) Results In Method (1): 1. Nucleotide in audory pathway inceased temporarilly and then decreased by sound stimulation. When Vitamin A was added, it increased much more. 2. Nucleotide in auditory pathway decreased by DHSM intoxication. In Method (2) : 1. In the cytoplasm and nucleus of the normal nerve cells, absorption at 260 m was observed. 2. In the uucleoli, an intense absorption at 280 m . was observed. 3. By sound stimulation, ribose nucleic acids in the cytoplasm increased temporarilly and then decreased. 4. The author drew the inferense that the mechanism in the formation of the nucleotide of the cytoplasm was irterfered by DHSM intoxication.
- 社団法人 日本耳鼻咽喉科学会の論文