内耳物質代謝の研究
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概要
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The changes in cochlear microphonics, were studied, after the injection of several kinds of solution into scala tympani of guineapigs, by modified Tasaki's method.Results are as follows:1)KCl alone is not the solution which reduces cochlear microphonics.MgCl2 reduces mi- crophonics more remarkably.And also high concentration, NaCl and CaCl2 reduce microphonics as well as KCl.2)E.D.T.A.which removes Ca ion from tissue, is also a strong microphonics reducing agent.but Hyaluronidase which increases permeability of the tissue is not effective on microphonics.even when it is used with other agents.3)Ace'tylcholin and Adrenalin do not reduce microphonics in ordinary concentration.Ten per cent cocain solution reduces microphonics remarkably.4)Cationic surface active agent reduces microphcnics most remarkably, and its 0.05%solution produces about 40db loss on microphonics.5)NaCN(10-1M), CH2JCOOH(5=10-2M)remarkably;NaCN(10-2M), maronic acid(10-2M), moderately;NaCN(10-4M), maronic acid(10-3M), D.N.P.(5=10-4M)slightly reduce the micro- phonics.
- 社団法人 日本耳鼻咽喉科学会の論文