ストマイ難聴の初期像に関する研究

概要

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One thausand and fortyfive cases which had been on Streptomycin therapy were examined and Streptomycin deafness was found in 8 to 12%. The relation between the amount of Streptomycin injected and the hearing loss in Streptom- ycin deafness were as follows: Genarally, hearing loss was seen at or higher than 8000c.p.s in the eary stage of Streptomycin deafness, total am ount of Streptomycin given being less than 40 grams. Extensive hearing loss in speech range was seen in cases which had showed hearing loss of more than 30db. at 800cps by less than 20 grams of Streptomycin and even though the therapy habbeen continued. Therefore, Streptomycin deafness can be prevented by discontinuing Streptomycin therapy whe hearing loss of more than 30db. is found at 8000cps when the total amount of 20 grams is given. In cases which do not show hearing loss of 30db. at 8000cps when the total amount of more than 20grams is given, full course of Streptomycin be given. This method of prevention of Streptomycin deafness was proved to be practical and effective by the authors clinical study in 1045 cases.
社団法人日本耳鼻咽喉科学会の論文