慢性中耳炎の細菌学的研究
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概要
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Clinical and laboratory studies on 104 cases of chronic otitis media were carried out.The results were as follows :1) Several kinds of non-pathogenic micro-organisms were isolated from 64 % of the control group (113 ears), and no micro-organisms was found in 36 % of them. The bacteria normally residing in the external ear canel was supposed to be Staph. epidermidis.2) The micro-organisms isolated from otorrhea were mainly Staph. aureus, Staph. epidermidis, Corynebacterium, P. aeruginosa, P. mirabilis, P, inconstans, etc3) Within several days after acute acceleration of chronic otitis media, Staph. aureus was isolated in most of cases. Genus Proteus, on the other hand, was isolated in a few cases.However, after two months from acute acceleration, Staph. aureus disappeared in most of cases and Genus Proteus apparently increased.4) The micro-organisms in otorrhea coincided with those at the nosopharynx in 42 % of the examined cases. The type of otitis media gave much influence upon the coincidence of the microorganisms between the middle ear cavity and the upper respiratory tract. Especially, otitis media with perforation at the pars tensa of the ear drum was greatly influenced by upper respiratory infection.5) Those cases which received bacterial examination within one month from the onset of acute acceleration showed u higher coincidence of the organisms isolated from the middle ear cavity and from the upper respiratory tract than those cases received the examination after one month from the onset.6) The cases accompanied by upper respiratory infection showed a higher coincidence of the micro-organisms between the middle ear cavity and the upper respiratory tract than those without upper respiratory infection.7) No influence of inoculum size of the micro-organisms on the examination for antibiotic sensitivity was found, if the type of strain was the same.
- 社団法人 日本耳鼻咽喉科学会の論文