鼻副鼻腔粘膜組織のLDH-isozymepatternと可溶性蛋白分画構成

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概要

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• The electrophoretic analysis of lactic acid dehydrogenase (LDH) in nasal and paranasal mucosa was estimated by Saitos method for LDH-isozymogram, and at the same time, the protein electrophoresis in the same tissues was performed, and the following results were obtained:1. The LDH isozyme pattern of nasal and paranasal mucosa contains all types of LDH isozyme from the type I to V, and trends to the M type (skeletal muscle type); the type IV of LDH holds the highest percentage in them.2, The LDH isozyme patterns of nasal mucosa, paranasal mucosa and nasal polypi are almost the same.3. The LDH isozyme pattern of nasal and paranasal mucosa differs from that of blood corpuscle and serum, but is similar to that, of the red bone marrow, the lung and the tonsil.4. With regard to 3 age groups (under 15, from 16 to 40, and over 41 years old), the components of the H type (heart muscle type) increase slightly in the nasal and paranasal mucosa of the age group under 15 years.5. With regard to the composition of soluble protein, albumine fraction decreases and *obulin fraction increases in the nasal and paranasal mucosa, compared with that of sera.6. The composition of soluble protein fraction in nasal polypi differs from that of nasal, and paranasal mucosa, but is similar to that of sera.7. The composition of soluble protein fraction in nasal and paranasal mucosa is lacking in variety with age.8. With regard to the LDH isozymogram and the protein electrophoresis from the same. nasal and paranasal mucosa, the type I of LDH isozyme is situated at the position of al-globulin fraction, the type II at that of a2-globulin fraction, the type III at that of β-globulin fraction, and the type IV and V at that of γ-globulin fraction.

• 社団法人 日本耳鼻咽喉科学会の論文

著者

• 野田 寛

  Department of Otorhinolaryngology, University of the Ryekylts,College of Health Science

• 都川 紀正

  Department of Otorhinolaryngology, University of the Ryekylts,College of Health Science

• 大木 剛

  Department of Otorhinolaryngology, University of the Ryekylts,College of Health Science

• 栗田 建一

  Department of Otorhinolaryngology, University of the Ryekylts,College of Health Science

• 喜友名 千佳子

  Department of Otorhinolaryngology, University of the Ryekylts,College of Health Science

• 陳 煥隆

  Department of Otorhinolaryngology, Nihon University,School of Medicine

関連論文

• 鼻副鼻腔粘膜組織のLDH-isozymepatternと可溶性蛋白分画構成
• 沖縄県における上咽頭悪性腫瘍の臨床的観察

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