全身転移をおこした鼻腔悪性黒色腫の1例

概要

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A case of malignant melanoma with wide hematogenic metastases was reported. The primary lesion was a pigmented tumor in the nasal cavity, originating from lower nasal turbinate, with repeated nasal bleeding. It was revealed by autopsy that there were two types of metastasis in malignant melanoma, one was melanotic type, with melanin pigment, and the other was amelanotic, without melanin pigment. Although these two types might be observed in the same organ, these were clearly separated to each other. Namely, two types were clearly differentiated and these were no evidence of transition of both types. The change observed in melanocyte; melanotic to amelanotic, might be influenced by radiation therapy in this paticular case.
社団法人日本耳鼻咽喉科学会の論文