扁桃性病巣感染における扁桃抽出液Hyaluronidase活性並びに血清中Hyaluronidase抑制物質についての研究

概要

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In the patients with focal chronic tonsillitis, the titer of HD extracted from palatine tonsils was higher than in those with simple chronic tonsillitis.In group of focal chronic tonsillitis high titer of HD (exceeded the overlimit of mean value of simple chronic tonsillitis.) was seen in 80-100% of cases by intradermal spreading method and in 40-100% of cases by turbidity reducing method.High titer of HD was generally seen in the heavy inflammatory cases.The serum HI titer before tonsillectomy had intimate relation with HD titer by turbidity reducing method.The serum HI before tonsillectomy showed high titer in focal group and to have some tendency to parallel with pathological changes of systemic disease.It was confirmed that serum HI had close relation to hypophyseal-adrenocortiticalsystem in mechanism of its fluctuation.In systemic disease with focal chronic tonsillitis, serum HI titer was decreased after tonsillectomy and paralleled with the course of systemic disease.In the cases of slight fever, serum HI titer was increased in parallel with body temperatiure rised after provocations with tonsil massage and HD-massage.From the facts mentioned above it was surmised that HD was accentuated by provocation in palatine tonsils and spread into humoral fluid with pathologic substances.
社団法人日本耳鼻咽喉科学会の論文