家兎口蓋扁桃の過剰刺激による脳波の変化

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Following a surgical maniplation of the pharyngeal area, as in tonsillectomy, development of a shock condition is frequently encountered.Reilly and others have attributed this particular type of shock to the irritation of the autonomic nerve of that area, through a certain type of reflex mechanism.The author observed the significant changes of electrical activity of the brain in electroencephalogram after the irritation of the tonsil of the rabbit with Croton Oil.The changes obtained are spike wave, increased frequency and decreased amplitude.Such changes of electroencepnalogram, on the other hand were greatly minimized when Chlorpromazine was administered beforehand in the appropriate dose and at the appropriate time.The results obtained are as follows.1) After injection of Croton Oil to the left tonsil, activating pattern was observed.2) Activating pattern was observed at the 3) No changes of the electroencephalogram was observed in the rabbit injected with Croton Oil to the abdominal skin. same time in most electrodes.4) Few changes of electroencephalogram was observed in cases in whicn Chlorpromazine was administered beforehand.5) Chlorpromazine gave no improvements on the electrical changes produced by the injection of Croton Oil. 6) The higher the activating pattern, the sooner the rabbit died.
社団法人日本耳鼻咽喉科学会の論文