体内汚染事故の応急処置に関する実験的研究

概要

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In this paper we described an experimental study on the first aid for the accidental intake of radionuclides. Following experiments on first aid were made: (1) Sodium Alignate or prussian blue was respectively given orally to the mice immediately after administration of 85Sr or 134Cs. (2) Isotonic saline intraperitoneal treatment as a type of water supply or DTPA oral treatment was made to the mice immediately after intravenous injection of 58Co or 54Mn. The whole body retention in mice was measured with a 5cm NaI(Tl) scintillation detector up to 28hr after administration. Sodium alginate or prussian blue reduced intestinal absorption of radiostrontium or radiocesium. DTPA and isotonic saline increased excretion of radiocobalt and radiomanganese in urine. DTPA oral treatment reduced the whole body retention of 58Co to 66% and 54Mn to 89% of the control. It was worked out from the dose estimation that the intraperitoneal injection of 10ml isotonic saline or DTPA oral administration immediately after 58Co injection decreased the internal radiation dose by approximately 22% or 14%, respectively.