4. Experimental and Clinical Studies of the Colonic Myoelectrical Activity
スポンサーリンク
概要
- 論文の詳細を見る
Experimental and clinical investigation of the colonic myoelectrogram was presented in this paper for the practical clinical evaluation.<BR>Experimentally, the similar myoelectrograms were obtained using both of the trans-peritoneal method and the anorectal method in the normal dogs. Furthermore, in the colon with segmental oligoganglionosis induced by temporal anoxia, the abnormal discharge of spike burst appeared in the involved segment and the distal side but not in the proximal side of the colon.<BR>Clinical studies of the colonic myoelectrogram by the anorectal approach were per-formed in 81 cases with disorders of the bowel movement and in 12 normal subjects. The frequent discharges of the spike burst have been recognized in the 74 cases of former group (91.4%) but not in control group. During the clinical course of the inflammatory colonic disease, the abnormal myoelectrical activity was recognized prior to the histopathological ag-gravation. Furthermore, the threshold against acetylcholin decreased significantly in the patients with the disorder of the bowel movement.<BR>In 19 cases with unknown caused disorder of bowel movement, the hyperlipemia and frequent discharge of spike burst were noticed in 16 cases suggesting that the abdominal symptoms accompanied with pain could be caused by the abnormal bowel peristalsis.
- 日本大腸肛門病学会の論文