Diffuse Panbronchiolitis and Rheumatoid Arthritis: A Possible Correlation with HLA-B54.
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概要
- 論文の詳細を見る
We analyzed the HLA antigens in two patients with rheumatoid arthritis accompanied by diffuse panbronchiolitis in whom HLA typing could be done and found the presence of B54 and DR4 alleles. We previously reported that the frequency of HLA-B54 is significantly increased in patients with diffuse panbronchiolitis. This allele demonstrates a linkage disequilibrium with DR4 (or DR4.1) in Japanese individuals. The association of rheumatoid arthritis with HLA-DR4 is well established in various ethnic groups including Japanese people. Since both diseases show the same pattern of HLA correlation, more Japanese patients with these two diseases are likely to be encountered.(Internal Medicine 33: 612-614, 1994)
- 社団法人 日本内科学会の論文
著者
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KITAMURA Satoshi
the Department of Pulmonary Medicine
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OHNO Shoji
the Division of Pulmonary Medicine, the Department of Medicine, Jichi Medical School
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SUGIYAMA Yukihiko
the Division of Pulmonary Medicine, the Department of Medicine, Jichi Medical School
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Kano Shogo
Division Of Rheumatology And Clinical Immunology Department Of Medicine Jichi Medical School
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Maeda Hiroo
Blood Transfusion Service Saitama Medical Center Saitama Medical School
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SUGIYAMA Yukihiko
The Department of Pulmonary Medicine, Jichi Medical School
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KANO Shogo
Division of Clinical Immunology, Jichi Medical School
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- Diffuse Panbronchiolitis and Rheumatoid Arthritis: A Possible Correlation with HLA-B54.
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