Incorporation of Adenosine and Adenosine Triphosphate into Rat Myocardium
スポンサーリンク
概要
- 論文の詳細を見る
The isolated rat heart is perfused with adenosine-8-C14, or a mixture of ATP-8-C14 and ATP-γ-P32 of known isotope (C14/P32) ratio. The results indicate that any difference between the rate of incorporation of adenosine-C14 or ATP-C14 into myocardial nucleosides and nucleotides fraction did not show significance, and also that any difference of the C14 distribution in the perfusates between adenosine-C14 and ATP-C14 perfused by the isolated rat hearts did not show singnificance.When perfused with C14-and P32-ATP of known isotope ratio, ATP isolated from the myocardium showed an isotope ratio (C14/P32) approximately 5 times greater than that of ATP in perfusion fluid.These results suggest that ATP might be first degraded and later resynthesized intracellularly.
- International Heart Journal刊行会の論文
著者
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Nakamura Motoomi
Reseach Institute Of Angiocardiology And Cardiovascular Clinic Faculty Of Medicine
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Miyazaki Tadashi
Research And Training Vessels Tokyo University Of Fisheries
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HATTORI Eizou
Research Institute of Angiocardiology, Kyushu University Medical School
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