Time Course of Left Ventricular Pressure-Volume Relationship under Various Enddiastolic Volume

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概要

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• A variable, e(t)=p(t)/v(t), is proposed for formulating the ventricular pumping of blood, as a concept of the reciprocal of ventricular compliance, where t=time, p(t)=time course of the intraventricular pressure and v(t)=that of the intraventricular volume. For actual computation, e(t)=p(t)/{v(o)-∫toi(t)dt} where v(o)=v(t) at t=o or enddiastolic volume and i(t)=aortic blood flow. v(o)=(1-ρ)-1•vs, where ρ=residual volume ratio measured by a thermodilution method and vs=stroke volume or integral of i(t) in the cardiac cycle. e(t) is calculated of areflexive left ventricles of dogs under various v(o) controlled by occlusion of the vena cava. In spite of conspicuous changes of p(t), i(t) and v(t), e(t) has ap-proximately unchanged time course and magnitude in a wide range of v(o). A model of ventricular pumping is presented with e(t).

• International Heart Journal刊行会の論文

著者

• SUGA Hiroyuki

  Institute for Medical and Dental Engineering, Tokyo Medical and Dental University

関連論文

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• Servocontrolled Computation of Instantaneous Aortic Blood Flow from Aortic Blood Pressure
• Time Course of Left Ventricular Pressure-Volume Relationship under Various Enddiastolic Volume
• Time Course of Left Ventricular Pressure-Volume Relationship under Various Extents of Aortic Occlusion
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