A Consideration on the Mechanism of Development of the Attack of the Variant Form of Angina Pectoris

スポンサーリンク

概要

• 論文の詳細を見る

• In view of the apparent contrast in clinical symptoms between the variant form of angina pectoris and conventional effort angina and of tendency towards the decrease of heart rate at the beginning of the former attack, an entirely different mechanism was assumed between these 2 diseases. Based on this assumption, 3 patients with this disease were studied from the viewpoint of catecholamines in blood. As the result, the decrease of catecholamines in blood, especially adrenaline, immediately before and at the beginning of attack, was established. Based on this fact, the mechanism of the development of the attack of the variant form of angina pectoris was explained by the temporary state of obstruction of the large branch of the coronary artery with advanced stenosis due to the increased tonus, following the weakening of the dilation effect of the coronary artery due to decrease of blood adrenaline at rest. The mechanism of development of specific clinical symptoms might be explained too by fluctuations of catecholamines in blood due to stress such as cardiac ischemia or anginal pain.

• International Heart Journal刊行会の論文

著者

• HANAZONO Naoto

  First Department of Internal Medicine, Faculty of Medicine, University of Tottori

• SHIMOYAMA Shoshi

  First Department of Internal Medicine, Faculty of Medicine, University of Tottori

• ANDO Yoshihiro

  First Department of Internal Medicine, Faculty of Medicine, University of Tottori

関連論文

• A Consideration on the Mechanism of Development of the Attack of the Variant Form of Angina Pectoris

スポンサーリンク