Effect of Ouabain on Calcium Ion Distribution in Cardiac Muscle on Electron Microscopic Level

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概要

• 論文の詳細を見る

• (1) Sodium dihydroxytartrate osazone added to a fixative solution was used for the subcellular localization of calcium ion in the cardiac muscle tissue. (2) In the control group of mice, the resulting precipitate distributed inside the terminal cisternae and in a lesser amount inside and around the longitudinal tubule of the sarcoplasmic reticulum. There were also occasional deposits in the myofibrils, especially over the Z line. (3) In the other group with administration of therapeutic ouabain dose (0.15μg.), the significantly increased amount of precipitate was observed in the same regions as in the control. (4) The increased calcium was considered to be exchangeable calcium and to be related to the inotropic action of the cardiac glycosides.

• International Heart Journal刊行会の論文

著者

• Shiina Shin-ichi

  Department Of Internal Medicine School Of Medicine Tokyo Medical And Dental University

• MIZUHIRA Vinci

  Laboratories for Hard Tissue Research, Department of Cell Biology, School of Medicine, Tokyo Medical

• Mizuhira Vinci

  Laboratories For Hard Tissue Research Department Of Cell Biology School Of Medicine Tokyo Medical An

• MIZUHIRA Vinci

  Laboratory of Cell Biology, Institute for Hard Tissue Research, School of Medicine, Tokyo Medical and Dental University

• SHIINA Shin-ichi

  Department of Internal Medicine, School of Medicine, Tokyo Medical and Dental University

関連論文

• Localization and Product-mechanism of the Tannic Acid : I. Demonstration of Tannic Acid in a Leaf of Tea-plant
• Effect of Ouabain on Calcium Ion Distribution in Cardiac Muscle on Electron Microscopic Level
• RELATION OF CALCIUM ION WITH INOTROPIC EFFECT ON SUBCELLULAR LEVEL : PROCEEDINGS OF THE 35TH ANNUAL MEETlNG OF THE JAPANESE CIRCULATION SOCIETY (Part III)

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