Observations on Several Experimental Models of Hypertension in Mice

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概要

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• A cuff and tail microphonic method (Friedman-Freed's technique) was applied to determine the systolic blood pressure of unanesthetized mice. It ranged from 94 to 132mm.Hg with a mean of 109mm.Hg. Chronic hypertension and hypertensive cardiovascular changes were induced in mice by a) constriction of unilateral renal artery with contralateral nephrectomy (Goldblatt), b) complete ligation of a branch of unilateral artery with contralateral nephrectomy (Loomis), c) unilateral adrenal enucleation with contralateral nephrectomy and adrenalectomy plus salt (Skelton), and by d) desoxycorticosterone acetate plus salt.

• International Heart Journal刊行会の論文

著者

• EBIHARA Akio

  Second Department of Internal Medicine, Faculty of Medicine, University of Tokyo

• MARTZ B.L.

  Lilly Laboratory for Clinical Research, Marion County General Hospital, Indianapolis

関連論文

• Observations on Several Experimental Models of Hypertension in Mice
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• Effects of Chronic Electrical Stimulation of Diencephalon on Aortas in Rabbits
• Effect of Uremic Human Plasma on Renin Activity

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