Deep Skin Infection of Scedosporium apiospermum in a Patient with Refractory Idiopathic Thrombocytopenic Purpura

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概要

• 論文の詳細を見る

• Infection of Scedosporium apiospermum is very rare but is now emerging as an important cause of both localized and disseminated infections in immunocompromised patients. A 62-year-old woman, who had undergone steroid therapy for refractory idiopathic thrombocytopenic purpura and had a history of diffuse large B cell lymphoma, developed a deep skin ulcer complicated with lymphangitis. After culture study demonstrated the presence of S. apiospermum, voriconazole (VRCZ) was administered and prompt improvement was observed. Because it is difficult to distinguish S. apiospermum from Aspergillus by histopathology and S. apiospermum is resistant to amphotericin B, VRCZ should be selected as the first choice of antifungal agent when mold is considered to be the causative organism.

著者

• FUJIWARA Yutaka

  Division of Internal Medicine, National Cancer Center Hospital

• Takeuchi Makoto

  Division Of Hematology Department Of Medicine Kobe University Graduate School Of Medicine

• Ota Yusuke

  Division of Orthopedics, National Hospital Organization Minami-Okayama Medical Center, Japan

• Yoshida Chikamasa

  Division of Hematology, National Hospital Organization Minami-Okayama Medical Center, Japan

関連論文

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• Deep Skin Infection of Scedosporium apiospermum in a Patient with Refractory Idiopathic Thrombocytopenic Purpura
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