Two Cases of Hypothyroidism Associated with Alpha-Interferon Therapy.
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概要
- 論文の詳細を見る
Alpha-interferon was used for anti-cancer or anti-viral therapy in two patients with preexisting Autoimmune thyroid disease and in seven patients with chronic viral hepatitis who had no history of thyroid dysfunction. Primary hypothyroidism developed in the two patients who had a history of autoimmune thyroid disease, while no changes in thyroid function were observed in the other seven patients. Modulation of the immune system by alpha-interferon may have been responsible for the development of hypothyroidism in these two patients. Therefore, autoantibodies to the thyroid and the thyroid function should be assessed in patients undergoing alpha-interferon therapy.(Internal Medicine 31 : 373-376, 1992)
- 社団法人 日本内科学会の論文
著者
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Onji Morikazu
The Third Department Of Internal Medicine Ehime University School Of Medicine
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Noguchi Shiro
Noguchi Thyroid Clinic & Hospital Foundation
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MASUMOTO Toshikazu
The Third Department of Internal Medicine, Ehime University School of Medicine
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Nakanishi Kimio
The Third Department Of Internal Medicine Ehime University School Of Medicine
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Taniguchi Yoshiyasu
The Third Department Of Internal Medicine Ehime University School Of Medicine
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MURAKAMI Tsukasa
the Third Department of Internal Medicine, Ehime University School of Medicine
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TAMAI Masatake
the Third Department of Internal Medicine, Ehime University School of Medicine
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MATSUUA Bunzo
the Third Department of Internal Medicine, Ehime University School of Medicine
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TAJIRI Junichi
Noguchi Thyroid Clinic and Hospital Foundation
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OHTA Yasuyuki
the Third Department of Internal Medicine, Ehime University School of Medicine
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