Abnormalities of Pulmonary Function in Patients with Non-insulin-Dependent Diabetes Mellitus.
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概要
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To examine the possible association between the vascular complications of diabetes and changes in pulmonary function, we performed pulmonary function tests including assessment of the diffusing capacity (%DLco) in 80 patients with non-insulin-dependent diabetes mellitu (45 males and 35 females) without overt lung or heart disease. The mean age of the subjects was 57.9 years and the mean duration of diabetes was 10.8 years. The %DLco decreased significantly as the duration of diabetes increased (r=-0.38, p<0.01), and the same relationship was also observed in non-smoking subjects (N=37). The reduction in %DLco was greater in patients with diabetic microangiopathy (especially nephropathy) and in those treated with insulin. Other pulmonary function tests (%VC, FEV1.0, PaO2 and PaCO2) showed no relationship to the duration of diabetes, the degree of microangiopathy or the type of treatment. These results suggest that diabetic microangiopathy may play an important role in the decrease of %DLco.(Internal Medicine 31 : 189-193, 1992)
- 社団法人 日本内科学会の論文
著者
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Yamakido Michio
The Second Department Of Internal Medicine Hiroshima University
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OKUBO Masamichi
the Second Department of Internal Medicine
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Yamane Kiminori
The Second Department Of Internal Medicine Hiroshima University School Of Medicine
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MORI Hiroshi
The Second Department of Internal Medicine, Hiroshima University School of Medicine
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KADO Seijiro
The Second Department of Internal Medicine, Hiroshima University School of Medicine
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OKAMURA Midori
The Second Department of Internal Medicine, Hiroshima University School of Medicine
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EGUSA Genshi
The Second Department of Internal Medicine, Hiroshima University School of Medicine
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HIRAMOTO Takehiko
The Second Department of Internal Medicine, Hiroshima University School of Medicine
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HARA Hitoshi
The Second Department of Internal Medicine, Hiroshima University School of Medicine
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