Mixed Connective Tissue Disease Associated with Protein Losing Enteropathy: Successful Treatment with Intravenous Cyclophosphamide Therapy.

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概要

• 論文の詳細を見る

• A patient with mixed connective tissue disease who developed protein losing enteropathy (PLE) is described. The PLE and other symptoms improved dramatically after monthly intravenous administration of 700 mg/day cyclophosphamide three times combined with oral prednisolone, while they were ineffective to the treatment with intravenous methyl-prednisolone 500 mg per day for 3 days. The serum level of CA125 antigen paralleled the severity of symptoms, signs and laboratory data associated with PLE. Thus, pleural effusion, ascites, edema and hypoalbuminemia improved along with the decrease in the level of CA125, suggesting that CA125 might be a marker of the activity of PLE.(Internal Medicine 31 : 1359-1362, 1992)

• 社団法人　日本内科学会の論文

著者

• DEMURA Hiroshi

  The Second Department of Medicine, Tokyo Women's Medical College

• SUZUKI Takahiro

  the Institute of Rheumatology, Tokyo Women's Medical College

• Kashiwazaki Sadao

  The Institute Of Rheumatology Tokyo Women's Medical College

• SATO Kanji

  the Second Department of Internal Medicine, Tokyo Women's Medical College

• ONODA Noritaka

  the Second Department of Internal Medicine, Tokyo Women's Medical College

• FURUYA Takefumi

  the Second Department of Internal Medicine, Tokyo Women's Medical College

• TAMURA Kazuko

  the Second Department of Internal Medicine, Tokyo Women's Medical College

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• Mixed Connective Tissue Disease Associated with Protein Losing Enteropathy: Successful Treatment with Intravenous Cyclophosphamide Therapy.

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