Malignant Lymphoma Localized in the Abdomen. Detection of Ig Gene Rearrangement from the Specimen Obtained by Percutaneous Lymph Node Biopsy.
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概要
- 論文の詳細を見る
A 32-year-old man was admitted to our hospital because of lumbago and an abdominal mass revealed by abdominal ultrasonography. Abdominal CT scan and MRI revealed multiple para-aortic lymph node swelling involving several arteries and veins. As there was no superficial lymph node swelling, percutaneous lymph node biopsy was performed under ultrasonographic guide. Although non-Hodgkin's lymphoma, diffuse, small cell type was suspected by light microscopic study, the monoclonality of the lymphocytes in the obtained specimen was not clear by the immunohistochemical study. Southern blot hybridization analysis of the biopsy specimen revealed the rearrangement of IgH and IgL (λ) chain gene, indicating the existence of monoclonal proliferation of lymphoma cells. The DNA analysis appears useful for the differential diagnosis of lympho-proliferative diseases.(Internal Medicine 31 : 1281-1285, 1992)
- 社団法人 日本内科学会の論文
著者
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Chou Takaaki
The Department Of Medicine (ii) Niigata University Medical School
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HAYASHI Naoki
the Department of Chemistry, Graduate School of Science, Nagoya University
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Ito Satoshi
The Department Of Medicine (ii) Niigata University School Of Medicine
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Arakawa Masaaki
The Department Of Internal Medicine(ii) Niigata University School Of Medicine
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IIRI Takao
the Department of Medicine (II), Niigata University Medical School
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KURASIGE Kazuyuki
the Department of Medicine (II), Niigata University Medical School
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WAKABAYASHI Masaya
the Department of Medicine (II), Niigata University Medical School
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- Malignant Lymphoma Localized in the Abdomen. Detection of Ig Gene Rearrangement from the Specimen Obtained by Percutaneous Lymph Node Biopsy.