Serum Interleukin-2 Receptor and Interferon-.ALPHA. Levels in a Patient with Allergic Granulomatous Angiitis (Churg-Strauss).

概要

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A patient with allergic granulomatous angiitis accompanied by increases in serum interleukin-2 receptor (IL-2R) and interferon-a (IFN-α) levels is reported. Laboratory findings revealed leukocytosis with eosinophilia and increased serum IgE and IgG. The serum IL-2R and IFN-α were increased. The serum immune complex, interferon-β, -γ and complements remained at normal levels. The serum IgE, IgG, IL-2R and IFN-α correlated with disease activity. Immunofluorescent studies using frozen sections obtained from the dermal lesion showed no immunoglobulin or complement deposits on vascular walls. Measurements of serum IL-2R and IFN-α might be considered reliable serologic indicators of disease activity.(Internal Medicine 31 : 955-959, 1992)
社団法人　日本内科学会の論文