Multiple Myeloma Complicated by Congestive Heart Failure Following First Administration of Recombinant .ALPHA.-Interferon.
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概要
- 論文の詳細を見る
A 59-year-old female was admitted to Tsukuba University Hospital and diagnosed as IgA-λ multiple myeloma (stage IIIA). No cardiovascular disorder with the exception of minor ischemic changes in ECG was revealed before treatment. Recombinant human α-interferon (IFN) at a dose of 3 million units combined with melphalan and prednisolone was administrated. Sixteen hours after the first administration of IFN, IFN was suspended by the symptoms of congestive heart failure (CHF). Treatment with diuretics and catecholamine products showed almost complete recovery from CHF in 3 weeks. An adverse reaction to IFN was strongly suspected as the cause of CHF.(Internal Medicine 31 : 936-940, 1992)
- 社団法人 日本内科学会の論文
著者
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HASEGAWA Yuichi
the Division of Hematology, Institute of Clinical Medicine, University of Tsukuba
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KOBAYASHI Toshitaka
the Division of Hematology, Institute of Clinical Medicine, University of Tsukuba
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NAGASAWA Toshiro
the Division of Hematology, Institute of Clinical Medicine, University of Tsukuba
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ABE Tsukasa
the Division of Hematology, Institute of Clinical Medicine, University of Tsukuba
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Sato Yuji
The Department Of Neuropsychiatry Nihon University School Of Medicine
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YODA Yasuhiro
the Division of Hematology, Institute of Clinical Medicine, University of Tsukuba
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SATO Yuji
the Department of Internal Medicine, Miyazaki Prefectual Hospital
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- Multiple Myeloma Complicated by Congestive Heart Failure Following First Administration of Recombinant .ALPHA.-Interferon.
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