Progressive External Ophthalmoplegia and Myositis.

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概要

• 論文の詳細を見る

• We reported a senile male patient with progressive external ophthalmoplegia (PEO) and myositis. The ophthalmoplegia was severe, but other neuromuscular features were nearly normal. Muscle enzymes in serum were moderately elevated. Autoimmune, endocrinological or malignant diseases were not observed during the previous 4 years. Pathology of non-weak limb muscles biopsied twice was consistent with active inflammatory myopathy. The ragged-red or cytochrome c oxidase-negative fibers, which are a hallmark of mitochondrial myopathy with PEO, were not increased in comparison with age-matched control muscles. Analysis of mitochondrial DNA in muscle by the Southern blot method did not reveal any deletions. It was concluded that the inflammatory myopathy, myositis clinically localized at the ocular muscles, is an important and distinct disorder in PEO.(Internal Medicine 32: 319-322, 1993)

• 社団法人　日本内科学会の論文

著者

• SAHASHI Ko

  Neurology Section, Fourth Department of Medicine, Aichi Medical University

• IBI Tohru

  Neurology Section, Fourth Department of Medicine, Aichi Medical University

• SUOH Hiroshi

  Neurology Section, Fourth Department of Medicine, Aichi Medical University

• TASHIRO Michinari

  Neurology Section, Fourth Department of Medicine, Aichi Medical University

• IBI Tohru

  Neurology Section, the Fourth Department of Medicine, Aichi Medical University

• SUOH Hiroshi

  Neurology Section, the Fourth Department of Medicine, Aichi Medical University

• TANAKA Fumiaki

  Neurology Section, the Fourth Department of Medicine, Aichi Medical University

• MITSUMA Terunori

  Neurology Section, the Fourth Department of Medicine, Aichi Medical University

• OHNO Kinji

  the Department of Neurology, Faculty of Medicine, University of Nagoya

関連論文

• Immunostaining of Dystrophin and Utrophin in Skeletal Muscle of Dystrophinopathies.
• Progressive External Ophthalmoplegia and Myositis.

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