Erythroderma and Marked Atypical Lymphocytosis Mimicking Cutaneous T-Cell Lymphoma Probably Caused by Phenobarbital.
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概要
- 論文の詳細を見る
A 56-year-old man had been treated with phenobarbital seven weeks prior to admission. One month after initiation of administration of phenobarbital, fever, skin rash and lymphadenopathy occurred. Nine days later, marked atypical lymphocytosis, eosinophilia and hepatic injury was noticed. The histology of the biopsied skin was indistinguishable from lymphoma. CHOP-therapy was started but the patient was followed without further treatment because of polyclonal T-lymphocytosis. Afterward, clinical and hematologic improvement ensued and he has been well until now, 52 months later. The marked T-lymphocytosis observed in this case is probably a lymphoid leukemoid reaction secondary to hypersensitivity to phenobarbital.(Internal Medicine 32: 182-184, 1993)
- 社団法人 日本内科学会の論文
著者
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Sakai Chikara
The Division Of Hematology And Chemotherapy Chiba Cancer Center Hospital
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Tanabe Nobuhiro
The Department Of Chest Medicine Chiba University School Of Medicine
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Takagi Toshiyuki
The Division Of Hematology And Chemotherapy
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WAKATSUKI Susumu
the Division of Internal Medicine, Chosei Public Hospital
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OGURO Masao
the Division of Hematology and Chemotherapy, Chiba Cancer Center Hospital
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- Erythroderma and Marked Atypical Lymphocytosis Mimicking Cutaneous T-Cell Lymphoma Probably Caused by Phenobarbital.