48,XXYY Syndrome Associated with Acromegaloidism.

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概要

• 論文の詳細を見る

• We report a case of double male syndrome, a type of Klinefelter's syndrome with 48, XXYY chromosome, associated with acromegaloidism. Although the patient presented acromegalic appearance, he did not show hypersecretion of growth hormone (GH). GH provocation tests revealed a rather low GH responses or no responses. After testosterone therapy, the GH responses were normalized except to Insulin tolerance test (ITT). On the other hand, the plasma corticotropin (ACTH) and cortisol levels were decreased paradoxically after hypoglycemia. Testosterone therapy did not restore this ACTH response. It was speculated that these abnormal GH and ACTH responses to hypoglycemia might indicate another congenital anomaly.(Internal Medicine 32: 160-165, 1993)

• 社団法人　日本内科学会の論文

著者

• YOSHIKAWA Masahide

  The Third Department of Internal Medicine, Nara Medical University

• Tsujii Tadasu

  The Third Department Of Internal Medicine Nara Medical University

• Okamoto Shingo

  The Third Department Of Internal Medicine Nara Medical University

• Fukui Hiroshi

  The Third Department Of Internal Medicine Nara Medical University

• YAMANE Yoshiko

  the Third Department of Internal Medicine, Nara Medical University

• MATSUMURA Yosinobu

  the Third Department of Internal Medicine, Nara Medical University

• TSUJITA Shigenobu

  the Third Department of Internal Medicine, Nara Medical University

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