A Diabetic Case of Hb Riyadh with a Low HbA1c Value.
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概要
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A 74-year-old male patient with diabetes mellitus and hypertension who had been treated for a long period was admitted to our hospital. Laboratory data on admission revealed high values for fasting blood sugar and fructosamine, 219 mg/dl and 389 μmol/l respectively, while the concentration of glycated hemoglobin (HbA1c) was low (3.0%). High performance liquid chromatography and isoelectric focusing analysis of the patient's Hb disclosed abnormal Hb with the content being 41.3%. The structural analysis indicated that this abnormal Hb was Hb Riyadh [β120 (GH3) Lys→Asn]. The low value of HbA1c despite the high blood glucose level may be attributed to this abnormal hemoglobin.(Internal Medicine 32: 128-132, 1993)
- 社団法人 日本内科学会の論文
著者
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TODA Gotaro
the First Department of Internal Medicine Jikei University School Medicine
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MAEZAWA Yoshihiko
the First Department of Internal Medicine, the Jikei University School of Medicine
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YAMAUCHI Masayoshi
the First Department of Internal Medicine, the Jikei University School of Medicine
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NAKABAYASHI Tomoko
the First Department of Internal Medicine, the Jikei University School of Medicine
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TOSHIMA Kyouichirou
the First Department of Internal Medicine, the Jikei University School of Medicine
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IKEDA Kiyoko
the Division of Clinical Laboratory, the Jikei University School of Medicine
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