Acute Lymphoblastic Leukemia Associated with a t(l;l9)(q23;pl3) in an Adult.
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概要
- 論文の詳細を見る
A cytogenetic study of a 38-year-old patient with acute lymphoblastic leukemia (ALL) revealed a t(1;19)(q23;pl3), which is a characteristic translocation of childhood ALL. The leukemic cells were positive for the CD10, CD19, HLA-DR, TdT and cytoplasmic μ-chain. Both of the immunoglobulin heavy chain gene loci were rearranged and the RNA-based polymerase chain reaction demonstrated the E2A/PBX1 fusion transcript which is the result of the t(1;19). This finding suggests that the t(l;19) is implicated not only in childhood ALL but also in adult ALL patients.(Internal Medicine 32: 584-587, 1993)
- 社団法人 日本内科学会の論文
著者
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Imanaka Takanobu
The Department Of Internal Medicine Tenri Hospital
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Akasaka Takashi
The Department Of Cardiology Kawasaki Medical University
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AMANO Hiroyuki
The Department of Hematology, Tenri Hospital
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KIKUCHI Masahiko
the Department of Clinical Pathology, Tenri Hospital and Tenri Medical Institute
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AKASAKA Takashi
the Division of Hematology, Tenri Hospital
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MASUYA Masahiro
the Division of Hematology, Tenri Hospital
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OHNO Hitoshi
the Division of Hematology, Tenri Hospital
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INOUE Tetsurou
the Division of Hematology, Tenri Hospital
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OKUMURA Atsuko
the Department of Clinical Pathology, Tenri Hospital and Tenri Medical Institute
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MIYANISHI Setsuko
the Department of Clinical Pathology, Tenri Hospital and Tenri Medical Institute
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OHASHI Isao
the Department of Clinical Pathology, Tenri Hospital and Tenri Medical Institute
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OHNO Yoh-ichirou
the Division of Hematology, Tenri Hospital
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INOUE Tetsurou
the Department of Cardiology, Tenri Hospital
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