Successful Treatment of Hypothyroid Graves' Disease with a Combination of Levothyroxine Replacement, Intravenous High-Dose Steroid and Irradiation to the Orbit.
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概要
- 論文の詳細を見る
A 46-year-old woman with hypothyroid Graves' disease (EMO syndrome) is reported. The patient had bilateral exophthalmos, conjunctival chemosis, periorbital edema and limitation of lateral gaze. Laboratory examination revealed the presence of primary hypothyroidism with positive thyroid-stimulating hormone (TSH) binding inhibitory immunoglobulin and thyroid stimulation antibody. These fiindings indicated a diagnosis of hypothyroid Graves' disease or EMO syndrome. She received levothyroxine replacement and steroid pulse therapy followed by radiotherapy. Her visual symptoms showed marked improvement and pretibial myxedema disappeared. Although several studies indicate that hypothyroid Graves' disease is a different entity from hyperthyroid Graves' disease, this report suggests that steroid pulse therapy combined with radiotherapy may be effective to treat ophthalmopathy in both diseases.(Internal Medicine 32: 421-423, 1993)
- 社団法人 日本内科学会の論文
著者
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Koshiyama Hiroyuki
The Division Of Endocrinology And Metabolism Department Of Internal Medicine Hyogo Prefectural Amaga
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Koh Toshikiyo
The Division Of Endocrinology Department Of Internal Medicine
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FUJIWARA Kazuhisa
the Department of Radiology, Kyoto City Hospital
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MORI Shigeki
the Division of Endocrinology, Department of Medicine, Kyoto City Hospital
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KOSHIYAMA Hiroyuki
the Division of Endocrinology, Department of Medicine, Kyoto City Hospital
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HAYAKAWA Katsumi
the Department of Radiology, Kyoto City Hospital
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- Successful Treatment of Hypothyroid Graves' Disease with a Combination of Levothyroxine Replacement, Intravenous High-Dose Steroid and Irradiation to the Orbit.